Predictive value of genetic diagnosis for cancer micrometastasis

Genetic determinants of lung cancer micrometastasis.

Predictive Value of Niacin Skin Sensitivity Test for the Diagnosis of Schizophrenia

Objective: To investigate niacin sensitivity in schizophrenia patients, meeting DSM-5 criteria for schizophrenia, as well as to healthy controls (HC) in order to examine the accuracy of niacin skin test in these patients. Methods: this was a diagnostic test accuracy study that conducted in 2018, Zanjan, Iran. We applied niacin patches of three concentrations (0.001 M, 0.01 M, and 0.1 M) to the...

Genetic diagnosis of cancer: diagnosis of mutations in BRCA1 and BRCA2 in breast cancer

During the last two decays the tremendous success in molecular biology and genetics which has surprised the entire world. So that today the sequencing of whole genome has been possible for each human individual to estimate its being affected with cardiovascular and cancer diseases. However, these achievements have some important limitations and deep ethical issues which might be ignored. Geneti...

Predictive value of radiological and clinical findings in early diagnosis of

Introduction: Invagination is the most common cause of acute abdomen and the second common cause of intestinal obstruction in the children under the age of two years, and the delay in diagnosis and treatment can be dangerous and even fatal. The aim of this study is to estimate the exact value of the diagnostic clinical and radiological findings in order to speed up the diagnosis of this emerg...

Rapid DNA Extraction Protocol from Stool, Suitable for Molecular Genetic Diagnosis of Colon Cancer

Colorectal cancer (CRC) is one of the most common forms of cancers in the world and is curable if diagnosed at the early stage. Analysis of DNA extracted from stool specimens is a recent advantage to cancer diagnostics. Many protocols have been recommended for DNA extraction from stool, and almost allof them are difficult and time consuming, dealing with high amount of toxic materials like phen...